Engineering in Medicine (EIM) research focuses on fundamental sciences, and developing innovative medical technologies and solutions to meet healthcare needs arising from major human diseases and an ageing population. Utilising bioengineering platforms, our research areas include advanced diagnostics and therapeutics, smart rehabilitative and monitoring system and devices. We establish close collaboration with clinicians to bring research from bench to bedside and continually developing collaborations with both international universities and local industry. Some of our faculty members are engaged in entrepreneurial activities, where they actively commercialise their developed technologies, either through licensing or via a new start-up. Research is underway to innovate new generation of tools and techniques which will change the way clinicians diagnose and treat patients. Efforts will be made to move from general therapy to personalised therapy, and from hospitalisation to home treatment and monitoring.
Currently, there are four main research themes under EIM research:
Considering the functional and structural complexity of brain and neural networks, the treatment of neuro disease remains tremendously challenging and existing medical technologies are far from sufficient. In NUS Engineering, we develop technology for basic neurosciences with the aim to understand the neural problems at the fundamental level and to develop tools for such in-depth studies. We also search for clinical biomarkers for neurodegradation through studying MRI brain anatomy and functions and real-time clinical measurements. Finally, we also develop care system for neuro-rehabilitation, such as assistive robots, intervention for cognition improvement and daily monitoring systems for improving the lives of patients. Our faculty colleagues are in close collaboration with Singapore Institute of Nuerotechnology (SINAPSE).
Therapeutics and Delivery Systems
We seek to obtain deeper fundamental understanding of drug physiology, so as to develop efficient and smart therapeutic delivery system which would have the following qualities, such as controlled release, active targeting, penetration through cellular barriers and multifunctionality. Ultimately, we aim to develop new generation nano-therapeutic devices and engineered neuro-therapy using multimodal delivery, for example, a new delivery system that can cross the blood-brain barrier to deliver drug in brain, will be explored in treating neuro-degenerative disease.
Point-of-Care Medical Devices
Our faculty members have excellent track record in developing point-of-care medical devices, which resulted in several spin-off companies. We aim to develop innovative medical technologies that can be used in a clinical setting for the diagnosis and treatment of various diseases, such as cancer, diabetes, stroke and cardiovascular diseases quickly, accurately and with high sensitivity.
We aim to develop advanced robotic system for performing surgery and assisting in medical procedure. Micro and Nano-robots may be developed for performing non-invasive surgery. Other robotics research area is also being developed, either for rehabilitation or as assistive devices.